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M94A3027.TXT
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1994-10-25
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Document 3027
DOCN M94A3027
TI Kaposi's sarcoma: a lymphoscintigraphic study of HIV-infected and
HIV-seronegative patients.
DT 9412
AU Cestari S da C; Petri V; Castiglioni ML; Alchorne MM; Katiki T; Escola
Paulista de Medicina, Sao Paulo, Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):170 (abstract no. PB0108). Unique
Identifier : AIDSLINE ICA10/94369548
AB OBJECTIVE: to evaluate extension of lymphatic involvement/damage in
cases of Kaposi's sarcoma (KS) of HIV-infected and non HIV-infected
individuals. A lymphologic perspective is focused to discuss correlation
between KS genesis and lymphatic disorder(s). METHODS:
Lymphoscintigraphy (radiolabeled 99mTc-Dextran intradermal injection)
was performed in three HIV-infected and two non-HIV-infected KS
patients. The legs of all cases were studied according the sites of KS
plaques. RESULTS: In all five cases there were clear lymphatic disorder
connection to KS tumors. The most common findings were: reduced
lymphatic drainage, collateral flow and dermal reflow. In cases of
severe lymphoedema lymphatics were not visualized after expected time.
CONCLUSION: Controversial genesis of KS makes lymphoscintigraphy an
useful method to study connection(s) between lymphologic disorders and
KS development. It can be employed to detect non suspected KS tumors, to
evaluate evolution and to amplify discussion about KS to be a disease of
lymphatic system.
DE Dextrans/DIAGNOSTIC USE Human HIV Infections/*RADIONUCLIDE IMAGING
Injections, Intradermal Leg Lymphatic Diseases/*RADIONUCLIDE IMAGING
Lymphedema/RADIONUCLIDE IMAGING Organotechnetium Compounds/DIAGNOSTIC
USE Prognosis Sarcoma, Kaposi's/*RADIONUCLIDE IMAGING Skin
Neoplasms/*RADIONUCLIDE IMAGING MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).